INSTALL.PROGRAMS: The Bioperl-run package has (Bio)perl wrappers written for the following applications: 1. Coils - Prediction of Coiled Coil Regions in Proteins Bio::Tools::Run::Coil http://www.ch.embnet.org/software/COILS_form.html 2. EMBOSS Applications - European Molecular Biology Open Software Suite Bio::Tools::Run::EMBOSSApplication http://www.hgmp.mrc.ac.uk/Software/EMBOSS/ 3. Eponine - Transcription Start Site finder Bio::Tools::Run::Eponine http://www.sanger.ac.uk/Software/analysis/eponine/ 4. FootPrinter - Program that performs phylogenetic footprinting. Bio::Tools::Run::FootPrinter http://abstract.cs.washington.edu/~blanchem/FootPrinterWeb/FootPrinterInput.pl 5. Genewise - Gene prediction program Bio::Tools::Run::Genewise http://www.sanger.ac.uk/software/wise2 6. Genscan - Identification of complete gene structures in genomic DNA Bio::Tools::Run::Genscan http://genes.mit.edu/GENSCAN.html 7. Hmmpfam - search a single sequence against an HMM database Bio::Tools::Run::Hmmpfam http://hmmer.wustl.edu/ 8. PISE - Web interfaces for Biological Programs Bio::Tools::Run::PiseApplication http://www-alt.pasteur.fr/~letondal/Pise/ 9. Primate - Near exact match finder for short sequence tags. Bio::Tools::Run:::Primate http://cvsweb.sanger.ac.uk/cgi-bin/cvsweb.cgi/ensembl-nci/?cvsroot=Ensembl 10. FingerPRINTScan - identify the closest matching PRINTS sequence motif fingerprints in a protein sequence Bio::Tools::Run::Prints http://www.bioinf.man.ac.uk/fingerPRINTScan/ 11. pfscan - scan a protein or DNA sequence with a profile library Bio::Tools::Run::Profile http://www.isrec.isb-sib.ch/software/software.html 12. Pseudowise - a pseudogene precdiction program, part of the wise2 package Bio::Tools::Run::Pseudowise http://www.sanger.ac.uk/software/wise2 13. RepeatMasker - screens DNA sequences in fasta format against a library of repetitive elements Bio::Tools::Run::RepeatMasker http://repeatmasker.genome.washington.edu 14. Seg - Identify low-complexity regions in protein sequences Bio::Tools::Run::Seg ftp://ftp.ncbi.nih.gov/pub/seg/ 15. Signalp - predicts the presence and location of signal peptide cleavage sites in amino acid sequences Bio::Tools::Run::Signalp http://www.cbs.dtu.dk/services/SignalP/ 16. Tmhmm - Prediction of transmembrane helices in proteins Bio::Tools::Run::Tmhmm http://www.cbs.dtu.dk/services/TMHMM/ 17. TribeMCL - Method for clustering proteins into related groups. Bio::Tools::Run::TribeMCL http://www.ebi.ac.uk/research/cgg/tribe/ 19. Molphy - MOLecular PHYlogenetics Package Bio::Tools::Run::Molphy http://www.ism.ac.jp/software/ismlib/softother.e.html 20. Phylip - Suite of Phylogenetics programs (Version 3.6) Bio::Tools::Run::Phylip http://evolution.genetics.washington.edu/phylip.html 22. DBA - DNA Block Aligner Bio::Tools::Run::Alignment::DBA http://www.sanger.ac.uk/software/wise2 23. Sim4 - Align CDNA to genomic sequences Bio::Tools::Run::Alignment::Sim4 http://globin.cse.psu.edu/ 25. BLAST - Basic Local Alignment Search Tool Bio::Tools::Run::StandAloneBlast (in bioperl-live CVS repository) ftp://ftp.ncbi.nih.gov/blast/executables 26. FASTA,SSEARCH - Pairwise sequence alignment Bio::Tools::Run::StandAloneFasta ftp://ftp.virginia.edu/pub/fasta 27. Promoterwise - Sequence alignment designed for promoter sequences http://www.sanger.ac.uk/software/wise2 28. Lagan - Lagan suite of tools including MLAGAN http://lagan.stanford.edu/ 29. Vista - Visualizing global DNA sequence alignments of arbitrary length http://www-gsd.lbl.gov/vista/VISTAdownload2.html 30. Exonerate - A package of alignment tools for protein and EST to genome/DNA alignments http://www.ebi.ac.uk/~guy/exonerate/ 31. AMAP- Protein multiple alignment based sequence annealing http://bio.math.berkeley.edu/amap/ 32. Blat - An alignment tool like BLAST, but structured differently http://genome.ucsc.edu/cgi-bin/hgBlat